A full range of hepatobiliary, pancreatic, endoscopic, radiological and surgical interventions are available. Management of patients with Hepatobiliary and Pancreatic Malignancy is co-ordinated through the weekly multi-disciplinary meeting. This has regular involvement from the: nine consultant surgeons three oncologists four radiologists one hepatologists two pathologists Royal Infirmary of Edinburgh Clinic A joint surgical/medical/oncology clinic is held at the Royal Infirmary of Edinburgh on a weekly basis on Tuesday afternoons. Approximately 120 liver resections per year are undertaken for primary and secondary tumours of the liver and proximal bile ducts. Major pancreatic resections and pancreatico-duodenectomy (approximately 60 per year) are undertaken for pancreatic cancer and distal cholangiocarcinoma. We also act a tertiary referral centre for the management of bile duct injuries, HPB trauma and patients with severe acute pancreatitis. Procedures A full range of endoscopic and interventional radiological procedures are available for the assessment and treatment of all pancreatico-biliary conditions. These procedures include: endoscopic retrograde cholangiopancreatography (ERCP) percutaneous transhepatic cholangiography (PTC) endoscopic ultrasound (EUS) spyglass chemoembolisation portal vein embolisation Laparoscopy Our advanced laparoscopic procedures include: staging of hepatobiliary and pancreatic malignancy de-roofing of liver cysts pancreatic and hepatic resections minimally invasive pancreatic necrosectomy Laparoscopic cholecystectomy and laparoscopic exploration of the common bile duct are also performed. This article was published on 2024-02-06